Creatinol O-Phosphate

Common Names: COP, Creatinolphosphate, Aplodan, Creatinol-O-phosphate

Scientific Names: 2-[Carbamimidoyl(methyl)amino]ethyl dihydrogen phosphate

Summary

Creatinol O-Phosphate (COP), also known as creatinol phosphate, is a synthetic analogue of creatine designed as a cardioprotective drug specifically for the treatment of heart complications. Administered through injections at a dosage of up to three grams, COP has shown promise in safeguarding cardiac cells, protecting against arrhythmia, and maintaining the integrity of cardiac tissue. Notably, research on COP is limited, and information on its oral consumption is scarce. Despite its potential benefits, the lack of recent studies and the absence of pharmacokinetic data make it challenging to fully understand the compound's efficacy and optimal dosing when taken orally. It is crucial to differentiate COP supplementation from traditional creatine supplementation, as COP metabolizes into creatinol rather than creatine. Moreover, it should not be confused with phosphocreatine. Although promising, the cessation of recent research raises questions about the compound's current standing in the realm of cardioprotective agents.