Ipamorelin is a synthetic peptide that belongs to the category of growth hormone-releasing peptides (GHRPs), specifically designed to stimulate the secretion of growth hormone (GH) from the pituitary gland. Structurally, it is a pentapeptide, meaning it is composed of five amino acids, which distinguish it as one of the most selective growth hormone secretagogues. Its mechanism of action involves mimicking the ghrelin hormone, binding to the ghrelin receptor in the brain, and stimulating the release of growth hormone in a GH pulse manner, thereby promoting an increase in natural GH levels without significantly affecting the levels of other hormones such as cortisol.
Ipamorelin is unique among similar compounds due to its specificity and selectivity for GH release, offering several potential benefits with comparatively fewer side effects. These benefits include:
Ipamorelin is typically administered through subcutaneous injections, allowing for direct absorption into the bloodstream. The dosing regimen can vary depending on the individual's goals, medical advice, and response to the peptide.
While ipamorelin is considered to have a favorable safety profile, particularly in terms of its limited influence on cortisol and prolactin levels, it is essential to approach its use with caution. As with any substance that influences hormone levels, potential side effects and contraindications should be thoroughly evaluated, ideally under the guidance of a healthcare professional. Moreover, the use of ipamorelin and similar peptides falls into a regulatory gray area in many jurisdictions, often being restricted to research purposes or requiring a prescription for legitimate medical use.